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Parallel roles of transcription factors dFOXO and FER2 in the development and maintenance of dopaminergic neurons
Forkhead box (FOXO) proteins are evolutionarily conserved, stress-responsive transcription factors (TFs) that can promote or counteract cell death. Mutations in FOXO genes are implicated in numerous pathologies, including age-dependent neurodegenerative disorders, such as Parkinson’s disease (PD). H...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864087/ https://www.ncbi.nlm.nih.gov/pubmed/29529025 http://dx.doi.org/10.1371/journal.pgen.1007271 |