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Efficient generation of functional haploid spermatids from human germline stem cells by three-dimensional-induced system

Generation of functional spermatids from human spermatogonial stem cells (SSCs) in vitro is of utmost importance for uncovering mechanisms underlying human germ cell development and treating infertility. Here we report a three-dimensional-induced (3D-I) system by which human SSCs were efficiently di...

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Detalles Bibliográficos
Autores principales: Sun, Min, Yuan, Qingqing, Niu, Minghui, Wang, Hong, Wen, Liping, Yao, Chencheng, Hou, Jingmei, Chen, Zheng, Fu, Hongyong, Zhou, Fan, Li, Chong, Gao, Shaorong, Gao, Wei-Qiang, Li, Zheng, He, Zuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864226/
https://www.ncbi.nlm.nih.gov/pubmed/29305586
http://dx.doi.org/10.1038/s41418-017-0015-1