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The membrane-distal regions of integrin α cytoplasmic domains contribute differently to integrin inside-out activation
Functioning as signal receivers and transmitters, the integrin α/β cytoplasmic tails (CT) are pivotal in integrin activation and signaling. 18 α integrin subunits share a conserved membrane-proximal region but have a highly diverse membrane-distal (MD) region at their CTs. Recent studies demonstrate...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864728/ https://www.ncbi.nlm.nih.gov/pubmed/29568062 http://dx.doi.org/10.1038/s41598-018-23444-w |