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Dual binding in cohesin-dockerin complexes: the energy landscape and the role of short, terminal segments of the dockerin module
The assembly of the polysaccharide degradating cellulosome machinery is mediated by tight binding between cohesin and dockerin domains. We have used an empirical model known as FoldX as well as molecular mechanics methods to determine the free energy of binding between a cohesin and a dockerin from...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864761/ https://www.ncbi.nlm.nih.gov/pubmed/29568013 http://dx.doi.org/10.1038/s41598-018-23380-9 |