Intravenous administration of anti-inflammatory mesenchymal stem cell spheroids reduces chronic alcohol intake and abolishes binge-drinking

Chronic alcohol intake leads to neuroinflammation and astrocyte dysfunction, proposed to perpetuate alcohol consumption and to promote conditioned relapse-like binge drinking. In the present study, human mesenchymal stem cells (MSCs) were cultured in 3D-conditions to generate MSC-spheroids, which gr...

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Detalles Bibliográficos
Autores principales: Ezquer, Fernando, Morales, Paola, Quintanilla, María Elena, Santapau, Daniela, Lespay-Rebolledo, Carolyne, Ezquer, Marcelo, Herrera-Marschitz, Mario, Israel, Yedy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864829/
https://www.ncbi.nlm.nih.gov/pubmed/29567966
http://dx.doi.org/10.1038/s41598-018-22750-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864829/
https://www.ncbi.nlm.nih.gov/pubmed/29567966
http://dx.doi.org/10.1038/s41598-018-22750-7

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