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Intravenous administration of anti-inflammatory mesenchymal stem cell spheroids reduces chronic alcohol intake and abolishes binge-drinking
Chronic alcohol intake leads to neuroinflammation and astrocyte dysfunction, proposed to perpetuate alcohol consumption and to promote conditioned relapse-like binge drinking. In the present study, human mesenchymal stem cells (MSCs) were cultured in 3D-conditions to generate MSC-spheroids, which gr...
Autores principales: | Ezquer, Fernando, Morales, Paola, Quintanilla, María Elena, Santapau, Daniela, Lespay-Rebolledo, Carolyne, Ezquer, Marcelo, Herrera-Marschitz, Mario, Israel, Yedy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864829/ https://www.ncbi.nlm.nih.gov/pubmed/29567966 http://dx.doi.org/10.1038/s41598-018-22750-7 |
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