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Taurine protects dopaminergic neurons in a mouse Parkinson’s disease model through inhibition of microglial M1 polarization

Microglia-mediated neuroinflammation is implicated in multiple neurodegenerative disorders, including Parkinson’s disease (PD). Hence, the modulatioein of sustained microglial activation may have therapeutic potential. This study is designed to test the neuroprotective efficacy of taurine, a major i...

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Detalles Bibliográficos
Autores principales: Che, Yuning, Hou, Liyan, Sun, Fuqiang, Zhang, Cong, Liu, Xiaofang, Piao, Fengyuan, Zhang, Dan, Li, Huihua, Wang, Qingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864871/
https://www.ncbi.nlm.nih.gov/pubmed/29568078
http://dx.doi.org/10.1038/s41419-018-0468-2