BEARscc determines robustness of single-cell clusters using simulated technical replicates

Single-cell messenger RNA sequencing (scRNA-seq) has emerged as a powerful tool to study cellular heterogeneity within complex tissues. Subpopulations of cells with common gene expression profiles can be identified by applying unsupervised clustering algorithms. However, technical variance is a majo...

Descripción completa

Detalles Bibliográficos
Autores principales: Severson, D. T., Owen, R. P., White, M. J., Lu, X., Schuster-Böckler, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864873/
https://www.ncbi.nlm.nih.gov/pubmed/29567991
http://dx.doi.org/10.1038/s41467-018-03608-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864873/
https://www.ncbi.nlm.nih.gov/pubmed/29567991
http://dx.doi.org/10.1038/s41467-018-03608-y

Ejemplares similares