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Human transbodies that interfere with the functions of Ebola virus VP35 protein in genome replication and transcription and innate immune antagonism

Small molecular inhibitors and passive immunization against Ebola virus disease (EVD) have been tested in animal models, including rodents and non-human primates, as well as in clinical trials. Nevertheless, there is currently no Food and Drug Administration (FDA)-approved therapy, and alternative s...

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Detalles Bibliográficos
Autores principales: Seesuay, Watee, Jittavisutthikul, Surasak, Sae-lim, Nawannaporn, Sookrung, Nitat, Sakolvaree, Yuwaporn, Chaicumpa, Wanpen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864874/
https://www.ncbi.nlm.nih.gov/pubmed/29568066
http://dx.doi.org/10.1038/s41426-018-0031-3