Bax retrotranslocation potentiates Bcl-x(L)’s antiapoptotic activity and is essential for switch-like transitions between MOMP competency and resistance

The rapid, typically all-or-none process of mitochondrial outer membrane permeabilization (MOMP) constitutes a primary cell death decision that is controlled by the Bcl-2 family interactome. However, how strict all-or-none MOMP decisions are governed by and emanate from the dynamic interplay of pro-...

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Detalles Bibliográficos
Autores principales: Hantusch, Annika, Das, Kushal K., García-Sáez, Ana J., Brunner, Thomas, Rehm, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864878/
https://www.ncbi.nlm.nih.gov/pubmed/29567940
http://dx.doi.org/10.1038/s41419-018-0464-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864878/
https://www.ncbi.nlm.nih.gov/pubmed/29567940
http://dx.doi.org/10.1038/s41419-018-0464-6

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