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Bax retrotranslocation potentiates Bcl-x(L)’s antiapoptotic activity and is essential for switch-like transitions between MOMP competency and resistance
The rapid, typically all-or-none process of mitochondrial outer membrane permeabilization (MOMP) constitutes a primary cell death decision that is controlled by the Bcl-2 family interactome. However, how strict all-or-none MOMP decisions are governed by and emanate from the dynamic interplay of pro-...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864878/ https://www.ncbi.nlm.nih.gov/pubmed/29567940 http://dx.doi.org/10.1038/s41419-018-0464-6 |