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Adjusting for Batch Effects in DNA Methylation Microarray Data, a Lesson Learned
It is well-known, but frequently overlooked, that low- and high-throughput molecular data may contain batch effects, i.e., systematic technical variation. Confounding of experimental batches with the variable(s) of interest is especially concerning, as a batch effect may then be interpreted as a bio...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864890/ https://www.ncbi.nlm.nih.gov/pubmed/29616078 http://dx.doi.org/10.3389/fgene.2018.00083 |