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Dnmt3a in the dorsal dentate gyrus is a key regulator of fear renewal

Renewal of extinguished fear memory in an altered context is widely believed to be a major limiting issue for exposure therapy in treating various psychiatric diseases. Effective prevention of fear renewal will significantly improve the efficacy of exposure therapy. DNA methyltransferase (DNMTs) med...

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Detalles Bibliográficos
Autores principales: Gong, Zhiting, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865109/
https://www.ncbi.nlm.nih.gov/pubmed/29572461
http://dx.doi.org/10.1038/s41598-018-23533-w