Iron regulatory protein deficiency compromises mitochondrial function in murine embryonic fibroblasts

Iron is essential for growth and proliferation of mammalian cells. The maintenance of cellular iron homeostasis is regulated by iron regulatory proteins (IRPs) through binding to the cognate iron-responsive elements in target mRNAs and thereby regulating the expression of target genes. Irp1 or Irp2-...

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Detalles Bibliográficos
Autores principales: Li, Huihui, Zhao, Hongting, Hao, Shuangying, Shang, Longcheng, Wu, Jing, Song, Chuanhui, Meyron-Holtz, Esther G., Qiao, Tong, Li, Kuanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865113/
https://www.ncbi.nlm.nih.gov/pubmed/29572489
http://dx.doi.org/10.1038/s41598-018-23175-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865113/
https://www.ncbi.nlm.nih.gov/pubmed/29572489
http://dx.doi.org/10.1038/s41598-018-23175-y

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