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Transcriptomic signatures of NK cells suggest impaired responsiveness in HIV-1 infection and increased activity post-vaccination

Natural killer (NK) cells limit viral replication by direct recognition of infected cells, antibody-dependent cellular cytotoxicity (ADCC), and releasing cytokines. Although growing evidence supports NK cell antiviral immunity in HIV-1 infection, further knowledge of their response is necessary. Her...

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Detalles Bibliográficos
Autores principales: Costanzo, Margaret C., Kim, Dohoon, Creegan, Matthew, Lal, Kerri G., Ake, Julie A., Currier, Jeffrey R., Streeck, Hendrik, Robb, Merlin L., Michael, Nelson L., Bolton, Diane L., Steers, Nicholas J., Eller, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865158/
https://www.ncbi.nlm.nih.gov/pubmed/29572470
http://dx.doi.org/10.1038/s41467-018-03618-w