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Concurrent action of purifying selection and gene conversion results in extreme conservation of the major stress-inducible Hsp70 genes in mammals

Several evolutionary mechanisms alter the fate of mutations and genes within populations based on their exhibited functional effects. To understand the underlying mechanisms involved in the evolution of the cellular stress response, a very conserved mechanism in the course of organismal evolution, w...

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Detalles Bibliográficos
Autores principales: Hess, Kyle, Oliverio, Ryan, Nguyen, Peter, Le, Dat, Ellis, Jacqueline, Kdeiss, Brianna, Ord, Sara, Chalkia, Dimitra, Nikolaidis, Nikolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865164/
https://www.ncbi.nlm.nih.gov/pubmed/29572464
http://dx.doi.org/10.1038/s41598-018-23508-x