Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo

Successive rounds of chemical modification in three generations of benzopyran molecules have shown to select for different mechanisms of actions and progressive increases in anti-cancer activity. In this study, we investigated the mechanism of action of the third-generation benzopyran compounds, TRX...

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Detalles Bibliográficos
Autores principales: Stevenson, Alexander J., Ager, Eleanor I., Proctor, Martina A., Škalamera, Dubravka, Heaton, Andrew, Brown, David, Gabrielli, Brian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865165/
https://www.ncbi.nlm.nih.gov/pubmed/29572477
http://dx.doi.org/10.1038/s41598-018-22882-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865165/
https://www.ncbi.nlm.nih.gov/pubmed/29572477
http://dx.doi.org/10.1038/s41598-018-22882-w

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