MultiBacMam Bimolecular Fluorescence Complementation (BiFC) tool-kit identifies new small-molecule inhibitors of the CDK5-p25 protein-protein interaction (PPI)

Protein-protein interactions (PPIs) are at the core of virtually all biological processes in cells. Consequently, targeting PPIs is emerging at the forefront of drug discovery. Cellular assays which closely recapitulate native conditions in vivo are instrumental to understand how small molecule drug...

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Detalles Bibliográficos
Autores principales: Bellón-Echeverría, Itxaso, Carralot, Jean-Philippe, Del Rosario, Andrea Araujo, Kueng, Stephanie, Mauser, Harald, Schmid, Georg, Thoma, Ralf, Berger, Imre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865166/
https://www.ncbi.nlm.nih.gov/pubmed/29572554
http://dx.doi.org/10.1038/s41598-018-23516-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865166/
https://www.ncbi.nlm.nih.gov/pubmed/29572554
http://dx.doi.org/10.1038/s41598-018-23516-x

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