Galantamine anti-colitic effect: Role of alpha-7 nicotinic acetylcholine receptor in modulating Jak/STAT3, NF-κB/HMGB1/RAGE and p-AKT/Bcl-2 pathways

Vagal stimulation controls systemic inflammation and modulates the immune response in different inflammatory conditions, including inflammatory bowel diseases (IBD). The released acetylcholine binds to alpha-7 nicotinic acetylcholine receptor (α7 nAChR) to suppress pro-inflammatory cytokines. This p...

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Detalles Bibliográficos
Autores principales: Wazea, Shakeeb A., Wadie, Walaa, Bahgat, Ashraf K., El-Abhar, Hanan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865178/
https://www.ncbi.nlm.nih.gov/pubmed/29572553
http://dx.doi.org/10.1038/s41598-018-23359-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865178/
https://www.ncbi.nlm.nih.gov/pubmed/29572553
http://dx.doi.org/10.1038/s41598-018-23359-6

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