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Functionalised Carbon Nanotubes Enhance Brain Delivery of Amyloid-Targeting Pittsburgh Compound B (PiB)-Derived Ligands

Alzheimer's disease (AD) is a neurodegenerative disorder characterised by brain accumulation of toxic protein aggregates, including extracellular amyloid beta (Aβ) plaques, inflammation, neuronal death and progressive cognitive dysfunction. Current diagnostic modalities, based on cognitive test...

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Detalles Bibliográficos
Autores principales: Costa, Pedro Miguel, Wang, Julie Tzu-Wen, Morfin, Jean-François, Khanum, Tamanna, To, Wan, Sosabowski, Jane, Tóth, Eva, Al-Jamal, Khuloud T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865270/
https://www.ncbi.nlm.nih.gov/pubmed/29577020
http://dx.doi.org/10.7150/ntno.23125