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Effects of Paclitaxel-conjugated N-Succinyl-Hydroxyethyl Chitosan Film for Proliferative Cholangitis in Rabbit Biliary Stricture Model

BACKGROUND: Paclitaxel (PTX) could inhibit the growth of fibroblasts, which occurs in proliferative cholangitis and leads to biliary stricture. However, its use has been limited due to poor bioavailability and local administration for short time. This study designed and synthesized a new PTX-conjuga...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Zou, Hao, Liu, Yun-Xia, Zhang, Xiao-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865316/
https://www.ncbi.nlm.nih.gov/pubmed/29521293
http://dx.doi.org/10.4103/0366-6999.226904