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The many faces of IKZF1 in B-cell precursor acute lymphoblastic leukemia

Transcription factor IKZF1 (IKAROS) acts as a critical regulator of lymphoid differentiation and is frequently deleted or mutated in B-cell precursor acute lymphoblastic leukemia. IKZF1 gene defects are associated with inferior treatment outcome in both childhood and adult B-cell precursor acute lym...

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Detalles Bibliográficos
Autores principales: Marke, René, van Leeuwen, Frank N., Scheijen, Blanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865415/
https://www.ncbi.nlm.nih.gov/pubmed/29519871
http://dx.doi.org/10.3324/haematol.2017.185603