Cargando…

The many faces of IKZF1 in B-cell precursor acute lymphoblastic leukemia

Transcription factor IKZF1 (IKAROS) acts as a critical regulator of lymphoid differentiation and is frequently deleted or mutated in B-cell precursor acute lymphoblastic leukemia. IKZF1 gene defects are associated with inferior treatment outcome in both childhood and adult B-cell precursor acute lym...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marke, René, van Leeuwen, Frank N., Scheijen, Blanca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ferrata Storti Foundation 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865415/ https://www.ncbi.nlm.nih.gov/pubmed/29519871 http://dx.doi.org/10.3324/haematol.2017.185603

Ejemplares similares

Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients
por: Scheijen, Blanca, et al.
Publicado: (2017)

Effect of IKZF1 deletions on signal transduction pathways in Philadelphia chromosome negative pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL)
por: van der Sligte, Naomi E, et al.
Publicado: (2015)

Reversal of IKZF1-induced glucocorticoid resistance by dual targeting of AKT and ERK signaling pathways
por: Butler, Miriam, et al.
Publicado: (2022)

IKZF1 deletion is associated with a poor outcome in pediatric B-cell precursor acute lymphoblastic leukemia in Japan
por: Asai, Daisuke, et al.
Publicado: (2013)

Changing of IKZF1 genotype during Philadelphia-negative precursor-B acute lymphoblastic leukemia progression: a short clinical report
por: Vshyukova, Volha, et al.
Publicado: (2016)

The Origin and Nature of Tightly Clustered BTG1 Deletions in Precursor B-Cell Acute Lymphoblastic Leukemia Support a Model of Multiclonal Evolution
por: Waanders, Esmé, et al.
Publicado: (2012)

Impact of IKZF1 Deletions in the Prognosis of Childhood Acute Lymphoblastic Leukemia in Argentina
por: Felice, María Sara, et al.
Publicado: (2022)

Prognostic impact of IKZF1 deletion in adults with common B-cell acute lymphoblastic leukemia
por: Yao, Qiu-Mei, et al.
Publicado: (2016)

Definition and Prognostic Value of Ph-like and IKZF1plus Status in Children With Down Syndrome and B-cell Precursor Acute Lymphoblastic Leukemia
por: Palmi, Chiara, et al.
Publicado: (2023)

The Prognostic Effect of IKZF1 Deletions in ETV6::RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia
por: Østergaard, Anna, et al.
Publicado: (2023)

Clinical and Genetic Characteristics of IKZF1 Mutation in Chinese Children With B-Cell Acute Lymphoblastic Leukemia
por: Zhang, Jingying, et al.
Publicado: (2022)

COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia
por: Lopes, Bruno Almeida, et al.
Publicado: (2016)

RAG1 high expression associated with IKZF1 dysfunction in adult B-cell acute lymphoblastic leukemia
por: Han, Qi, et al.
Publicado: (2019)

An investigation of methylation pattern changes in the IKZF1 promoter in patients with childhood B-cell acute lymphoblastic leukemia
por: Rahmani, Mina, et al.
Publicado: (2019)

Detection of Pathogenic Isoforms of IKZF1 in Leukemic Cell Lines and Acute Lymphoblastic Leukemia Samples: Identification of a Novel Truncated IKZF1 Transcript in SUP-B15
por: Zhao, Weiqiang, et al.
Publicado: (2020)

RCSD1-ABL1 Translocation Associated with IKZF1 Gene Deletion in B-Cell Acute Lymphoblastic Leukemia
por: Kamran, Shawana, et al.
Publicado: (2015)

IKZF1 deletions associate with CRLF2 overexpression leading to a poor prognosis in B-cell precursor acute lymphoblastic leukaemia
por: Maciel, Ana Luiza Tardem, et al.
Publicado: (2021)

IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia
por: Lopes, Bruno A., et al.
Publicado: (2019)

Confirmation of Childhood Acute Lymphoblastic Leukemia Variants, ARID5B and IKZF1, and Interaction with Parental Environmental Exposures
por: Evans, Tiffany-Jane, et al.
Publicado: (2014)

ARID5B, IKZF1 and Non-Genetic Factors in the Etiology of Childhood Acute Lymphoblastic Leukemia: The ESCALE Study
por: Rudant, Jérémie, et al.
Publicado: (2015)

P390: ALLO-HSCT OR CHEMOTHERAPY FOR B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA IN THE FIRST COMPLETE REMISSION: IMPACT OF MRD AND IKZF1
por: Deng, Shiyu, et al.
Publicado: (2023)

An Allele of IKZF1 (Ikaros) Conferring Susceptibility to Childhood Acute Lymphoblastic Leukemia Protects Against Type 1 Diabetes
por: Swafford, Austin D.-E., et al.
Publicado: (2011)

Advances in B-cell Precursor Acute Lymphoblastic Leukemia Genomics
por: Schwab, Claire, et al.
Publicado: (2018)

Upfront Treatment Influences the Composition of Genetic Alterations in Relapsed Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia
por: Yu, Jiangyan, et al.
Publicado: (2020)

The clinical impact of IKZF1 mutation in acute myeloid leukemia
por: Zhang, Xiang, et al.
Publicado: (2023)

High CRLF2 expression associates with IKZF1 dysfunction in adult acute lymphoblastic leukemia without CRLF2 rearrangement
por: Ge, Zheng, et al.
Publicado: (2016)

Case Report: Rare IKZF1 Gene Fusions Identified in Neonate with Congenital KMT2A-Rearranged Acute Lymphoblastic Leukemia
por: Eadie, Laura N., et al.
Publicado: (2023)

Lenalidomide induces degradation of IKZF1 and IKZF3
por: Krönke, Jan, et al.
Publicado: (2014)

Epigenetic Control of Infant B Cell Precursor Acute Lymphoblastic Leukemia
por: de Barrios, Oriol, et al.
Publicado: (2021)

Galectin-1 and Galectin-3 in B-Cell Precursor Acute Lymphoblastic Leukemia
por: Fei, Fei, et al.
Publicado: (2022)

The specific distribution pattern of IKZF1 mutation in acute myeloid leukemia
por: Zhang, Xiang, et al.
Publicado: (2020)

P397: IKZF1 ALTERATIONS HAVE A NEGATIVE IMPACT ON EARLY MOLECULAR RESPONSE AND SURVIVAL OF ADULT PATIENTS WITH B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA TREATED WITH GMALL 07/2003 PROTOCOL IN CZECHIA
por: Polivkova, Vaclava, et al.
Publicado: (2023)

Association of IKZF1 and CDKN2A gene polymorphisms with childhood acute lymphoblastic leukemia: a high-resolution melting analysis
por: Sattarzadeh Bardsiri, Mahla, et al.
Publicado: (2022)

JAK2 aberrations in childhood B-cell precursor acute lymphoblastic leukemia
por: Steeghs, Elisabeth M.P., et al.
Publicado: (2017)

S113: IMPACT OF IKZF1 DELETION IN RELAPSED AND/OR REFRACTORY B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA TREATED WITH CD19-CHIMERIC ANTIGEN RECEPTOR T-CELL THERAPY
por: Cai, Zihong, et al.
Publicado: (2023)

Altered neutrophil immunophenotypes in childhood B-cell precursor acute lymphoblastic leukemia
por: Oliveira, Elen, et al.
Publicado: (2016)

Erythroleukemia Relapsing as Precursor B-cell Lymphoblastic Leukemia
por: Park, Borae G., et al.
Publicado: (2011)

New genetics and diagnosis of childhood B-cell precursor acute lymphoblastic leukemia
por: Harrison, Christine
Publicado: (2011)

Glycoproteome remodeling in MLL-rearranged B-cell precursor acute lymphoblastic leukemia
por: Oliveira, Tiago, et al.
Publicado: (2021)

Hypercalcemia As the Sole Initial Presentation of Precursor B-cell Acute Lymphoblastic Leukemia
por: Trikannad Ashwini Kumar, Anup Kumar, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_h7fjhnsv8hv09di0bt2ociq6hq