Cargando…

Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome

Obesity enhances the risk of developing myelodysplastic syndromes. However, the effect of obesity on survival is unclear. Obese people present with monocytosis due to inflammatory signals emanating from obese adipose tissue. We hypothesized that obesity-induced myelopoiesis would promote the transit...

Descripción completa

Detalles Bibliográficos
Autores principales: Kraakman, Michael J., Kammoun, Helene L., Dragoljevic, Dragana, Al-Sharea, Annas, Lee, Man K.S., Flynn, Michelle C., Stolz, Christian J., Guirguis, Andrew A., Lancaster, Graeme I., Chin-Dusting, Jaye, Curtis, David J., Murphy, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865427/
https://www.ncbi.nlm.nih.gov/pubmed/29371326
http://dx.doi.org/10.3324/haematol.2017.181958