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Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome
Obesity enhances the risk of developing myelodysplastic syndromes. However, the effect of obesity on survival is unclear. Obese people present with monocytosis due to inflammatory signals emanating from obese adipose tissue. We hypothesized that obesity-induced myelopoiesis would promote the transit...
Autores principales: | Kraakman, Michael J., Kammoun, Helene L., Dragoljevic, Dragana, Al-Sharea, Annas, Lee, Man K.S., Flynn, Michelle C., Stolz, Christian J., Guirguis, Andrew A., Lancaster, Graeme I., Chin-Dusting, Jaye, Curtis, David J., Murphy, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865427/ https://www.ncbi.nlm.nih.gov/pubmed/29371326 http://dx.doi.org/10.3324/haematol.2017.181958 |
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