High-Dose Deferoxamine Treatment Disrupts Intracellular Iron Homeostasis, Reduces Growth, and Induces Apoptosis in Metastatic and Nonmetastatic Breast Cancer Cell Lines

Mounting evidence suggest that iron overload enhances cancer growth and metastasis; hence, iron chelation is being increasingly used as part of the treatment regimen in patients with cancer. Now whether iron chelation depletes intracellular iron and/or disrupts intracellular iron homeostasis is yet...

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Detalles Bibliográficos
Autores principales: Bajbouj, Khuloud, Shafarin, Jasmin, Hamad, Mawieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865460/
https://www.ncbi.nlm.nih.gov/pubmed/29562821
http://dx.doi.org/10.1177/1533033818764470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865460/
https://www.ncbi.nlm.nih.gov/pubmed/29562821
http://dx.doi.org/10.1177/1533033818764470

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