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Sensitization of P2X3 receptors in insular cortex contributes to visceral pain of adult rats with neonatal maternal deprivation

AIMS: Insular cortex is a brain region critical for processing of the sensation. Purinergic receptors are involved in the formation of chronic pain. The aim of the present study was to explore the role and mechanism of P2X3 receptors (P2X3Rs) in insular cortex in chronic visceral pain. METHODS: Chro...

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Detalles Bibliográficos
Autores principales: Zhang, Ping-An, Zhu, Hong-Yan, Xu, Qi-Ya, Du, Wan-Jie, Hu, Shufen, Xu, Guang-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865518/
https://www.ncbi.nlm.nih.gov/pubmed/29560791
http://dx.doi.org/10.1177/1744806918764731