Prostate-specific PTen deletion in mice activates inflammatory microRNA expression pathways in the epithelium early in hyperplasia development

PTen loss is one of the most frequent events in prostate cancer both at the initiation stage and during late stage metastatic development. The mouse model of prostate-specific probasin-mediated Pten deletion leads to prostate intraepithelial neoplasia (PIN) leading to adenocarcinoma. Using this mode...

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Detalles Bibliográficos
Autores principales: Dart, D. Alwyn, Uysal-Onganer, Pinar, Jiang, W. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865543/
https://www.ncbi.nlm.nih.gov/pubmed/29284790
http://dx.doi.org/10.1038/s41389-017-0007-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865543/
https://www.ncbi.nlm.nih.gov/pubmed/29284790
http://dx.doi.org/10.1038/s41389-017-0007-5

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