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Central IGF1 improves glucose tolerance and insulin sensitivity in mice

Insulin-like growth factor 1 (IGF1) is a key factor for tissue growth and fuel metabolism. The potential function of central IGF1 remains unclear. We previously observed that IGF1 expression is increased in the hypothalamus of obese mice lacking STAT5 in the central nervous system (CNS). In this stu...

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Detalles Bibliográficos
Autores principales: Hong, Hao, Cui, Zhen-Zhong, Zhu, Lu, Fu, Shu-Ping, Rossi, Mario, Cui, Ying-Hong, Zhu, Bing-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865549/
https://www.ncbi.nlm.nih.gov/pubmed/29259155
http://dx.doi.org/10.1038/s41387-017-0002-0