Cargando…

Central IGF1 improves glucose tolerance and insulin sensitivity in mice

Insulin-like growth factor 1 (IGF1) is a key factor for tissue growth and fuel metabolism. The potential function of central IGF1 remains unclear. We previously observed that IGF1 expression is increased in the hypothalamus of obese mice lacking STAT5 in the central nervous system (CNS). In this stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hong, Hao, Cui, Zhen-Zhong, Zhu, Lu, Fu, Shu-Ping, Rossi, Mario, Cui, Ying-Hong, Zhu, Bing-Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865549/ https://www.ncbi.nlm.nih.gov/pubmed/29259155 http://dx.doi.org/10.1038/s41387-017-0002-0

Ejemplares similares

Correction to: Central IGF1 improves glucose tolerance and insulin sensitivity in mice
por: Hong, Hao, et al.
Publicado: (2021)

Circadian misalignment alters insulin sensitivity during the light phase and shifts glucose tolerance rhythms in female mice
por: Zhong, Li-Xin, et al.
Publicado: (2019)

Maternal Glucose Tolerance in Pregnancy Affects Fetal Insulin Sensitivity
por: Luo, Zhong-Cheng, et al.
Publicado: (2010)

Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons
por: Farias Quipildor, Gabriela, et al.
Publicado: (2021)

Improved Insulin Sensitivity during Pioglitazone Treatment Is Associated with Changes in IGF-I and Cortisol Secretion in Type 2 Diabetes and Impaired Glucose Tolerance
por: Arnetz, Lisa, et al.
Publicado: (2013)

Study of insulin resistance in relation to serum IGF-I levels in subjects with different degrees of glucose tolerance
por: Martha, Srinivas, et al.
Publicado: (2008)

Insulin-like Growth Factor-2 (IGF-2) in Fibrosis
por: Zhu, Yuhan, et al.
Publicado: (2022)

Associations among IGF-1, IGF2, IGF-1R, IGF-2R, IGFBP-3, insulin genetic polymorphisms and central precocious puberty in girls
por: Chang, Hua-Pin, et al.
Publicado: (2018)

Glucose- and temperature-sensitive nanoparticles for insulin delivery
por: Wu, Jun-Zi, et al.
Publicado: (2017)

Regional Variations of Insulin Secretion and Insulin Sensitivity in Japanese Participants With Normal Glucose Tolerance
por: Watanabe, Kiriko, et al.
Publicado: (2021)

Stimulatory Effect of Insulin on Glucose Uptake by Muscle Involves the Central Nervous System in Insulin-Sensitive Mice
por: Coomans, Claudia P., et al.
Publicado: (2011)

Delay in glucose peak time during the oral glucose tolerance test as an indicator of insulin resistance and insulin secretion in type 2 diabetes patients
por: Wang, Xinlei, et al.
Publicado: (2018)

A simple intravenous glucose tolerance test for assessment of insulin sensitivity
por: Hahn, Robert G, et al.
Publicado: (2011)

Effects of Proximal Gut Bypass on Glucose Tolerance and Insulin Sensitivity in Humans
por: Breitman, Igal, et al.
Publicado: (2013)

Effects of Exercise Alone on Insulin Sensitivity and Glucose Tolerance in Obese Youth
por: Lee, SoJung, et al.
Publicado: (2013)

Sensitization and translocation of TRPV1 by insulin and IGF-I
por: Van Buren, Jeremy J, et al.
Publicado: (2005)

Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity
por: Yang, Shi-Bing, et al.
Publicado: (2011)

Shift of Glucose Peak Time During Oral Glucose Tolerance Test is Associated with Changes in Insulin Secretion and Insulin Sensitivity After Therapy with Antidiabetic Drugs in Patients with Type 2 Diabetes
por: Jiang, Yanqiu, et al.
Publicado: (2021)

A Fasting Insulin–Raising Allele at IGF1 Locus Is Associated with Circulating Levels of IGF-1 and Insulin Sensitivity
por: Mannino, Gaia Chiara, et al.
Publicado: (2013)

Natural History of Insulin Sensitivity and Insulin Secretion in the Progression From Normal Glucose Tolerance to Impaired Fasting Glycemia and Impaired Glucose Tolerance: The Inter99 Study
por: Færch, Kristine, et al.
Publicado: (2009)

Glucose tolerance and insulin sensitivity define adipocyte transcriptional programs in human obesity
por: Gerlini, R., et al.
Publicado: (2018)

Determining insulin sensitivity from glucose tolerance tests in Iberian and landrace pigs
por: Rodríguez-López, José Miguel, et al.
Publicado: (2021)

Changes in Insulin Sensitivity and Insulin Release in Relation to Glycemia and Glucose Tolerance in 6,414 Finnish Men
por: Stančáková, Alena, et al.
Publicado: (2009)

Long-Term Follow-Up of Oral Glucose Tolerance Test–Derived Glucose Tolerance and Insulin Secretion and Insulin Sensitivity Indexes in Subjects With Glucokinase Mutations (MODY2)
por: Martin, Delphine, et al.
Publicado: (2008)

Insulin sensitivity obtained from the oral glucose tolerance test and its relationship with birthweight
por: Dallar, Yıldız, et al.
Publicado: (2007)

In Vivo Insulin Sensitivity and Secretion in Obese Youth: What are the differences between normal glucose tolerance, impaired glucose tolerance, and type 2 diabetes?
por: Bacha, Fida, et al.
Publicado: (2009)

Review: Glucose-sensitive insulin
por: Hoeg-Jensen, Thomas
Publicado: (2020)

IGF-I Bioactivity in an Elderly Population: Relation to Insulin Sensitivity, Insulin Levels, and the Metabolic Syndrome
por: Brugts, Michael P., et al.
Publicado: (2010)

Adipocyte G(i) signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity
por: Wang, Lei, et al.
Publicado: (2020)

Central insulin‐like growth factor‐1 (IGF‐1) restores whole‐body insulin action in a model of age‐related insulin resistance and IGF‐1 decline
por: Huffman, Derek M., et al.
Publicado: (2015)

Effect of Intravenous Glucose Tolerance Test on Bone Turnover Markers in Adults with Normal Glucose Tolerance
por: Xiang, Shou-Kui, et al.
Publicado: (2016)

Effects of Insulin on Brain Glucose Metabolism in Impaired Glucose Tolerance
por: Hirvonen, Jussi, et al.
Publicado: (2011)

Central sensitivity to thyroid hormones is reduced in youths with overweight or obesity and impaired glucose tolerance
por: Di Bonito, Procolo, et al.
Publicado: (2023)

OR31-05 Long-Term Effects Of Gender Affirming Hormone Therapy On Insulin Sensitivity, Insulin Secretion, And Glucose Tolerance
por: Pinkson, Sheila, et al.
Publicado: (2023)

Estimates of Insulin Sensitivity Using Glucose and C-Peptide From the Hyperglycemia and Adverse Pregnancy Outcome Glucose Tolerance Test
por: Radaelli, Tatjana, et al.
Publicado: (2010)

Effect of a Successful Intensive Lifestyle Program on Insulin Sensitivity and Glucose Tolerance in Obese Youth
por: Shaw, Melissa, et al.
Publicado: (2009)

Advantages of the single delay model for the assessment of insulin sensitivity from the intravenous glucose tolerance test
por: Panunzi, Simona, et al.
Publicado: (2010)

Insulin secretion and sensitivity during oral glucose tolerance test in Korean lean elderly women.
por: Kim, J., et al.
Publicado: (2001)

The Role of Helicobacter pylori Seropositivity in Insulin Sensitivity, Beta Cell Function, and Abnormal Glucose Tolerance
por: Malamug, Lou Rose, et al.
Publicado: (2014)

Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance
por: Wickenberg, Jennie, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_c2omavbmi1e4u0mbj8gtqtat8s