Hsp90 inhibitor NMS-E973 exerts the anticancer effect against glioblastoma via induction of PUMA-mediated apoptosis

BACKGROUND: Glioblastoma is one of the most aggressive and common malignancies of the central nervous system in humans. Owing to the correlation of high Hsp90 expression with prognosis and clinical pathology features of diverse types of cancer, targeting Hsp90 with small-molecule inhibitors has beco...

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Detalles Bibliográficos
Autores principales: Sun, Libo, Yang, Shoujun, Chi, Guonan, Jin, Xingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865573/
https://www.ncbi.nlm.nih.gov/pubmed/29593424
http://dx.doi.org/10.2147/OTT.S160813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865573/
https://www.ncbi.nlm.nih.gov/pubmed/29593424
http://dx.doi.org/10.2147/OTT.S160813

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