RUNX1 and RUNX3 protect against YAP-mediated EMT, stem-ness and shorter survival outcomes in breast cancer

Hippo pathway target, YAP has emerged as an important player in solid tumor progression. Here, we identify RUNX1 and RUNX3 as novel negative regulators of oncogenic function of YAP in the context of breast cancer. RUNX proteins are one of the first transcription factors identified to interact with Y...

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Detalles Bibliográficos
Autores principales: Kulkarni, Madhura, Tan, Tuan Zea, Syed Sulaiman, Nurfarhanah Bte, Lamar, John M., Bansal, Prashali, Cui, Jianzhou, Qiao, Yiting, Ito, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865662/
https://www.ncbi.nlm.nih.gov/pubmed/29581836
http://dx.doi.org/10.18632/oncotarget.24419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865662/
https://www.ncbi.nlm.nih.gov/pubmed/29581836
http://dx.doi.org/10.18632/oncotarget.24419

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