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Mandatory role of HMGA1 in human airway epithelial normal differentiation and post-injury regeneration

Due to high levels of expression in aggressive tumors, high mobility group AT-hook 1 (HMGA1) has recently attracted attention as a potential anti-tumor target. However, HMGA1 is also expressed in normal somatic progenitor cells, raising the question: how might systemic anti-HMGA1 therapies affect th...

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Detalles Bibliográficos
Autores principales: Zhang, Haijun, Yang, Jing, Walters, Matthew S., Staudt, Michelle R., Strulovici-Barel, Yael, Salit, Jacqueline, Mezey, Jason G., Leopold, Philip L., Crystal, Ronald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865673/
https://www.ncbi.nlm.nih.gov/pubmed/29581847
http://dx.doi.org/10.18632/oncotarget.24511