Cargando…

Mandatory role of HMGA1 in human airway epithelial normal differentiation and post-injury regeneration

Due to high levels of expression in aggressive tumors, high mobility group AT-hook 1 (HMGA1) has recently attracted attention as a potential anti-tumor target. However, HMGA1 is also expressed in normal somatic progenitor cells, raising the question: how might systemic anti-HMGA1 therapies affect th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Haijun, Yang, Jing, Walters, Matthew S., Staudt, Michelle R., Strulovici-Barel, Yael, Salit, Jacqueline, Mezey, Jason G., Leopold, Philip L., Crystal, Ronald G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865673/ https://www.ncbi.nlm.nih.gov/pubmed/29581847 http://dx.doi.org/10.18632/oncotarget.24511

Ejemplares similares

Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression
por: Buro-Auriemma, Lauren J, et al.
Publicado: (2013)

Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium
por: Zhang, Haijun, et al.
Publicado: (2020)

Biologic Phenotyping of the Human Small Airway Epithelial Response to Cigarette Smoking
por: Tilley, Ann E., et al.
Publicado: (2011)

Genes associated with MUC5AC expression in small airway epithelium of human smokers and non-smokers
por: Wang, Guoqing, et al.
Publicado: (2012)

Waterpipe smoking induces epigenetic changes in the small airway epithelium
por: Walters, Matthew S., et al.
Publicado: (2017)

Smoking-mediated up-regulation of GAD67 expression in the human airway epithelium
por: Wang, Guoqing, et al.
Publicado: (2010)

Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD Risk Locus 19q13.2
por: Ryan, Dorothy M., et al.
Publicado: (2014)

High Correlation of the Response of Upper and Lower Lobe Small Airway Epithelium to Smoking
por: Harvey, Ben-Gary, et al.
Publicado: (2013)

RNA-Seq quantification of the human small airway epithelium transcriptome
por: Hackett, Neil R, et al.
Publicado: (2012)

Reply to Sharma and Zeki: Does Vaping Increase Susceptibility to COVID-19?
por: Zhang, Haijun, et al.
Publicado: (2020)

Up-regulation of ACE2, the SARS-CoV-2 receptor, in asthmatics on maintenance inhaled corticosteroids
por: O’Beirne, Sarah L., et al.
Publicado: (2021)

Smoking shifts human small airway epithelium club cells toward a lesser differentiated population
por: Rostami, Mahboubeh R., et al.
Publicado: (2021)

Cell-specific expression of lung disease risk-related genes in the human small airway epithelium
por: Zuo, Wu-lin, et al.
Publicado: (2020)

Role of KRAS in regulating normal human airway basal cell differentiation
por: Ogawa, Fumihiro, et al.
Publicado: (2019)

Persistence of Smoking-Induced Dysregulation of MiRNA Expression in the Small Airway Epithelium Despite Smoking Cessation
por: Wang, Guoqing, et al.
Publicado: (2015)

High apoptotic endothelial microparticle levels measured in asthma with elevated IgE and eosinophils
por: Strulovici-Barel, Yael, et al.
Publicado: (2023)

Down-Regulation of the Canonical Wnt β-Catenin Pathway in the Airway Epithelium of Healthy Smokers and Smokers with COPD
por: Wang, Rui, et al.
Publicado: (2011)

The Human Airway Epithelial Basal Cell Transcriptome
por: Hackett, Neil R., et al.
Publicado: (2011)

Intermittent exposure to whole cigarette smoke alters the differentiation of primary small airway epithelial cells in the air-liquid interface culture
por: Gindele, Julia A., et al.
Publicado: (2020)

Smoking accelerates aging of the small airway epithelium
por: Walters, Matthew S, et al.
Publicado: (2014)

Altered lung biology of healthy never smokers following acute inhalation of E-cigarettes
por: Staudt, Michelle R., et al.
Publicado: (2018)

Characterization of an immortalized human small airway basal stem/progenitor cell line with airway region-specific differentiation capacity
por: Wang, Guoqing, et al.
Publicado: (2019)

Basal cell origins of smoking-induced airway epithelial disorders
por: Shaykhiev, Renat, et al.
Publicado: (2014)

CREB-dependent LPA-induced signaling initiates a pro-fibrotic feedback loop between small airway basal cells and fibroblasts
por: Nathan, Shyam, et al.
Publicado: (2021)

Inferring genome-wide patterns of admixture in Qataris using fifty-five ancestral populations
por: Omberg, Larsson, et al.
Publicado: (2012)

Copy number variations in the genome of the Qatari population
por: Fakhro, Khalid A., et al.
Publicado: (2015)

Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity
por: Walters, Matthew S, et al.
Publicado: (2013)

Differentiated muscles are mandatory for gas-filling of the Drosophila airway system
por: Wang, Yiwen, et al.
Publicado: (2015)

Human airway xenograft models of epithelial cell regeneration
por: Puchelle, Edith, et al.
Publicado: (2000)

Airway epithelial regeneration requires autophagy and glucose metabolism
por: Li, Kuan, et al.
Publicado: (2019)

Airway management following head and neck microvascular reconstruction: is tracheostomy mandatory?
por: Madgar, Ory, et al.
Publicado: (2021)

Identifying novel associations in GWAS by hierarchical Bayesian latent variable detection of differentially misclassified phenotypes
por: Shafquat, Afrah, et al.
Publicado: (2020)

Activation of NOTCH1 or NOTCH3 Signaling Skews Human Airway Basal Cell Differentiation toward a Secretory Pathway
por: Gomi, Kazunori, et al.
Publicado: (2015)

The Qatar genome: a population-specific tool for precision medicine in the Middle East
por: Fakhro, Khalid A, et al.
Publicado: (2016)

Smoking Is Associated with Shortened Airway Cilia
por: Leopold, Philip L., et al.
Publicado: (2009)

Exome Sequencing of Only Seven Qataris Identifies Potentially Deleterious Variants in the Qatari Population
por: Rodriguez-Flores, Juan L., et al.
Publicado: (2012)

HMGA2 induces epithelial-to-mesenchymal transition in human hepatocellular carcinoma cells
por: LUO, YIZHOU, et al.
Publicado: (2013)

Role of High Tibial Osteotomy in Cartilage Regeneration – Is Correction of Malalignment Mandatory for Success?
por: Thambiah, Matthew Dhanaraj, et al.
Publicado: (2017)

Airways exudation of plasma macromolecules: Innate defense, epithelial regeneration, and asthma
por: Persson, Carl
Publicado: (2019)

Airway regeneration using iPS cell-derived airway epithelial cells with Cl(-) channel function
por: Yoshie, Susumu, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_tp6t97cnlo033uce8jmok428r6