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Fibroblast growth factor receptor signaling plays a key role in transformation induced by the TMPRSS2/ERG fusion gene and decreased PTEN

Prostate cancer is the most common visceral malignancy and the second leading cause of cancer deaths in US men. Correlative studies in human prostate cancers reveal a frequent association of the TMPRSS2/ERG (TE) fusion gene with loss of PTEN and studies in mouse models reveal that ERG expression and...

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Detalles Bibliográficos
Autores principales: Shao, Longjiang, Wang, Jianghua, Karatas, Omer Faruk, Feng, Shu, Zhang, Yiqun, Creighton, Chad J., Ittmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865682/
https://www.ncbi.nlm.nih.gov/pubmed/29581856
http://dx.doi.org/10.18632/oncotarget.24470