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Galectin-3 sensitized melanoma cell lines to vemurafenib (PLX4032) induced cell death through prevention of autophagy

Melanoma is a current worldwide problem, as its incidence is increasing. In the last years, several studies have shown that melanoma cells display high levels of autophagy, a self-degradative process that can promote survival leading to drug resistance. Consequently, autophagy regulation represents...

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Detalles Bibliográficos
Autores principales: Bustos, Silvina Odete, da Silva Pereira, Gustavo José, de Freitas Saito, Renata, Gil, Cristiane Damas, Zanatta, Daniela Bertolli, Smaili, Soraya Soubhi, Chammas, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865690/
https://www.ncbi.nlm.nih.gov/pubmed/29581864
http://dx.doi.org/10.18632/oncotarget.24516