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Development of an improved RT-qPCR Assay for detection of Japanese encephalitis virus (JEV) RNA including a systematic review and comprehensive comparison with published methods

BACKGROUND: Japanese encephalitis virus (JEV) is a major cause of encephalitis in Asia, and the commonest cause of mosquito-borne encephalitis worldwide. Detection of JEV RNA remains challenging due to the characteristic brief and low viraemia, with 0–25% of patients positive, and the mainstay of di...

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Detalles Bibliográficos
Autores principales: Bharucha, Tehmina, Sengvilaipaseuth, Onanong, Vongsouvath, Manivanh, Vongsouvath, Malavanh, Davong, Viengmon, Panyanouvong, Phonepasith, Piorkowski, Géraldine, Garson, Jeremy A., Newton, Paul N., de Lamballerie, Xavier, Dubot-Pérès, Audrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865736/
https://www.ncbi.nlm.nih.gov/pubmed/29570739
http://dx.doi.org/10.1371/journal.pone.0194412