Tanshinone IIA induces apoptosis via inhibition of Wnt/β-catenin/MGMT signaling in AtT-20 cells

A strategy to suppress the expression of the DNA repair enzyme O(6)-methylguanine-DNA methyltransferase (MGMT) by inhibition of Wnt/β-catenin signaling may be useful as a novel treatment for pituitary adenoma. Previous studies have reported that Tanshinone IIA (TSA), a major quinone compound isolate...

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Detalles Bibliográficos
Autores principales: Li, Zong-Yang, Huang, Guo-Dong, Chen, Lei, Zhang, Ce, Chen, Bao-Dong, Li, Qing-Zhong, Wang, Xiang, Zhang, Xie-Jun, Li, Wei-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865768/
https://www.ncbi.nlm.nih.gov/pubmed/28849207
http://dx.doi.org/10.3892/mmr.2017.7325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865768/
https://www.ncbi.nlm.nih.gov/pubmed/28849207
http://dx.doi.org/10.3892/mmr.2017.7325

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