Cargando…

Tanshinone IIA induces apoptosis via inhibition of Wnt/β-catenin/MGMT signaling in AtT-20 cells

A strategy to suppress the expression of the DNA repair enzyme O(6)-methylguanine-DNA methyltransferase (MGMT) by inhibition of Wnt/β-catenin signaling may be useful as a novel treatment for pituitary adenoma. Previous studies have reported that Tanshinone IIA (TSA), a major quinone compound isolate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zong-Yang, Huang, Guo-Dong, Chen, Lei, Zhang, Ce, Chen, Bao-Dong, Li, Qing-Zhong, Wang, Xiang, Zhang, Xie-Jun, Li, Wei-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865768/ https://www.ncbi.nlm.nih.gov/pubmed/28849207 http://dx.doi.org/10.3892/mmr.2017.7325

Ejemplares similares

Tanshinone IIA promotes the proliferation of WB-F344 hepatic oval cells via Wnt/β-catenin signaling
por: ZE, XINGYU, et al.
Publicado: (2016)

Tanshinone IIA promotes cardiac differentiation and improves cell motility by modulating the Wnt/β-catenin signaling pathway
por: Li, Kun, et al.
Publicado: (2020)

Tanshinone IIA inhibits glucose metabolism leading to apoptosis in cervical cancer
por: Liu, Zhigang, et al.
Publicado: (2019)

Tanshinone IIA: A Review of its Anticancer Effects
por: Fang, Zhong‐ying, et al.
Publicado: (2021)

Preparation and characterisation of solid dispersions of tanshinone IIA, cryptotanshinone and total tanshinones
por: Zhai, Xifeng, et al.
Publicado: (2017)

Effect of Supplementation of Tanshinone IIA and Sodium Tanshinone IIA Sulfonate on the Anticancer Effect of Epirubicin: An In Vitro Study
por: Chan, Szu-Erh, et al.
Publicado: (2011)

Effect of tanshinone IIA on cardiomyocyte hypertrophy and apoptosis in spontaneously hypertensive rats
por: JIANG, F.L., et al.
Publicado: (2013)

Transgelin-2 Involves in the Apoptosis of Colorectal Cancer Cells Induced by Tanshinone-IIA
por: Zhang, Yingru, et al.
Publicado: (2022)

The Attenuation of Traumatic Brain Injury via Inhibition of Oxidative Stress and Apoptosis by Tanshinone IIA
por: Huang, Yongpan, et al.
Publicado: (2020)

Tanshinone IIA inhibits cell viability and promotes PUMA-mediated apoptosis of oral squamous cell carcinoma
por: Han, Shuangze, et al.
Publicado: (2023)

Tanshinone IIA alleviates chondrocyte apoptosis and extracellular matrix degeneration by inhibiting ferroptosis
por: Xu, Jin, et al.
Publicado: (2023)

Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats
por: Yan, Jun, et al.
Publicado: (2016)

The Molecular Mechanisms of Tanshinone IIA on the Apoptosis and Arrest of Human Esophageal Carcinoma Cells
por: Wang, Jiang-Feng, et al.
Publicado: (2014)

Tanshinone IIA Inhibits Growth of Keratinocytes through Cell Cycle Arrest and Apoptosis: Underlying Treatment Mechanism of Psoriasis
por: Li, Fu-Lun, et al.
Publicado: (2012)

Characterization and Stability of Tanshinone IIA Solid Dispersions with Hydroxyapatite
por: Wang, Xiaopan, et al.
Publicado: (2013)

Renoprotective Effects of Tanshinone IIA: A Literature Review
por: Chen, Zhengtao, et al.
Publicado: (2023)

Metabolism of Tanshinone IIA, Cryptotanshinone and Tanshinone I from Radix Salvia Miltiorrhiza in Zebrafish
por: Wei, Yingjie, et al.
Publicado: (2012)

Sodium Tanshinone IIA Sulfonate Attenuates Erectile Dysfunction in Rats with Hyperlipidemia
por: Zhong, Liren, et al.
Publicado: (2020)

Kinetics of cytochrome P450 enzymes for metabolism of sodium tanshinone IIA sulfonate in vitro
por: Ouyang, Dong-sheng, et al.
Publicado: (2016)

Pharmacological Activity and Mechanism of Tanshinone IIA in Related Diseases
por: Guo, Rui, et al.
Publicado: (2020)

Tanshinone IIA Ameliorates Nonalcoholic Steatohepatitis in Mice by Modulating Neutrophil Extracellular Traps and Hepatocyte Apoptosis
por: Xu, Lianjie, et al.
Publicado: (2022)

Tanshinone IIA: A Promising Natural Cardioprotective Agent
por: Shang, Qinghua, et al.
Publicado: (2012)

Tanshinone IIA and hepatocellular carcinoma: A potential therapeutic drug
por: Li, Hu, et al.
Publicado: (2023)

Analysis of tanshinone IIA induced cellular apoptosis in leukemia cells by genome-wide expression profiling
por: Liu, Chang, et al.
Publicado: (2012)

Anti-Inflammatory and Immunomodulatory Mechanism of Tanshinone IIA for Atherosclerosis
por: Chen, Zhuo, et al.
Publicado: (2014)

Effect of tanshinone IIA on oxidative stress and apoptosis in a rat model of fatty liver
por: Yang, Guan-Lin, et al.
Publicado: (2017)

Influence of Tanshinone IIA on apoptosis of human esophageal carcinoma Eca‐109 cells and its molecular mechanism
por: Zhang, Yan, et al.
Publicado: (2017)

Sodium Tanshinone IIA Sulfonate Attenuates Tumor Oxidative Stress and Promotes Apoptosis in an Intermittent Hypoxia Mouse Model
por: Zhang, Xiao-Bin, et al.
Publicado: (2020)

Neuron Regeneration and Proliferation Effects of Danshen and Tanshinone IIA
por: Shen, Jui-Lung, et al.
Publicado: (2011)

Corrigendum to “Sodium Tanshinone IIA Sulfonate Attenuates Erectile Dysfunction in Rats with Hyperlipidemia”
por: Zhong, Liren, et al.
Publicado: (2020)

Evaluation of Tanshinone IIA Developmental Toxicity in Zebrafish Embryos
por: Wang, Tao, et al.
Publicado: (2017)

Effect of Tanshinone IIA on Gut Microbiome in Diabetes-Induced Cognitive Impairment
por: Zheng, Yanfang, et al.
Publicado: (2022)

Tanshinone IIA attenuates atherosclerosis via inhibiting NLRP3 inflammasome activation
por: Wen, Jiexia, et al.
Publicado: (2020)

Tanshinone IIA Protects Against Cardiac Hypertrophy via Inhibiting Calcineurin/Nfatc3 Pathway
por: Tan, Xueying, et al.
Publicado: (2011)

Tanshinone IIA Inhibits Epithelial-to-Mesenchymal Transition Through Hindering β-Arrestin1 Mediated β-Catenin Signaling Pathway in Colorectal Cancer
por: Song, Qing, et al.
Publicado: (2020)

Tanshinone IIA alleviates atherosclerosis in LDLR(−/−) mice by regulating efferocytosis of macrophages
por: Wang, Jiarou, et al.
Publicado: (2023)

Antifatigue properties of tanshinone IIA in mice subjected to the forced swimming test
por: Lin, Chueh-Yu, et al.
Publicado: (2017)

Protective effect of tanshinone IIA against cardiac hypertrophy in spontaneously hypertensive rats through inhibiting the Cys-C/Wnt signaling pathway
por: Feng, Jun, et al.
Publicado: (2016)

Sodium tanshinone IIA sulfonate stimulated Cl(−) secretion in mouse trachea
por: Chen, Peng-Xiao, et al.
Publicado: (2017)

Corrigendum: Tanshinone IIA Inhibits Epithelial-to-Mesenchymal Transition Through Hindering β-Arrestin1 Mediated β-Catenin Signaling Pathway in Colorectal Cancer
por: Song, Qing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_97pvh7vvdrr2cleh0vef7uj7ke