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Identification of TNFSF13, SPATC1L, SLC22A25 and SALL4 as novel susceptibility loci for atrial fibrillation by an exome-wide association study

An exome-wide association study (EWAS) was performed to identify genetic variants, particularly low-frequency or rare coding variants with a moderate to large effect size, that confer susceptibility to atrial fibrillation in Japanese. The EWAS for atrial fibrillation was performed with 13,166 subjec...

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Detalles Bibliográficos
Autores principales: Yamada, Yoshiji, Sakuma, Jun, Takeuchi, Ichiro, Yasukochi, Yoshiki, Kato, Kimihiko, Oguri, Mitsutoshi, Fujimaki, Tetsuo, Horibe, Hideki, Muramatsu, Masaaki, Sawabe, Motoji, Fujiwara, Yoshinori, Taniguchi, Yu, Obuchi, Shuichi, Kawai, Hisashi, Shinkai, Shoji, Mori, Seijiro, Arai, Tomio, Tanaka, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865780/
https://www.ncbi.nlm.nih.gov/pubmed/28849223
http://dx.doi.org/10.3892/mmr.2017.7334