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Construction of a lentiviral vector containing shRNA targeting ADAM17 and its role in attenuating endotoxemia in mice
Systemic inflammatory response syndrome is a pathophysiological inflammatory response mediated largely by tumor necrosis factor-α (TNF-α), in response to infectious or non-infectious stimuli. TNF-α secretion in response to bacterial lipopolysaccharide (LPS) is regulated in part by disintegrin and me...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865799/ https://www.ncbi.nlm.nih.gov/pubmed/28849138 http://dx.doi.org/10.3892/mmr.2017.7307 |