Cargando…

Construction of a lentiviral vector containing shRNA targeting ADAM17 and its role in attenuating endotoxemia in mice

Systemic inflammatory response syndrome is a pathophysiological inflammatory response mediated largely by tumor necrosis factor-α (TNF-α), in response to infectious or non-infectious stimuli. TNF-α secretion in response to bacterial lipopolysaccharide (LPS) is regulated in part by disintegrin and me...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Bing, Li, Xiaoou, Hu, Tuo, Lian, Wenjing, Zhang, Mingxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865799/
https://www.ncbi.nlm.nih.gov/pubmed/28849138
http://dx.doi.org/10.3892/mmr.2017.7307