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Molecular characterization of a pedigree carrying the hypertension-associated mitochondrial tRNA(Gln) T4363C mutation

Mitochondrial DNA mutations have been reported to be associated with essential hypertension. The present study reported the clinical and molecular features of a Chinese pedigree with maternally inherited hypertension. A total of 6 matrilineal relatives in this pedigree presented with variable degree...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Dong, Zhibing, Lin, Wenhui, Gao, Ranran, Chen, Caiming, Xu, Jinzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865805/
https://www.ncbi.nlm.nih.gov/pubmed/28849157
http://dx.doi.org/10.3892/mmr.2017.7371