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Efficient inhibition of duck hepatitis B virus DNA by the CRISPR/Cas9 system

Current therapeutic strategies cannot eradicate hepatitis B virus covalently closed circular DNA (HBV cccDNA), which accounts for the persistence of HBV infection. Very recently, the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) system has been...

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Detalles Bibliográficos
Autores principales: Zheng, Qingfen, Bai, Li, Zheng, Sujun, Liu, Mei, Zhang, Jinyan, Wang, Ting, Xu, Zhongwei, Chen, Yu, Li, Jiansheng, Duan, Zhongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865846/
https://www.ncbi.nlm.nih.gov/pubmed/28944845
http://dx.doi.org/10.3892/mmr.2017.7518