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Efficient inhibition of duck hepatitis B virus DNA by the CRISPR/Cas9 system
Current therapeutic strategies cannot eradicate hepatitis B virus covalently closed circular DNA (HBV cccDNA), which accounts for the persistence of HBV infection. Very recently, the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) system has been...
Autores principales: | Zheng, Qingfen, Bai, Li, Zheng, Sujun, Liu, Mei, Zhang, Jinyan, Wang, Ting, Xu, Zhongwei, Chen, Yu, Li, Jiansheng, Duan, Zhongping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865846/ https://www.ncbi.nlm.nih.gov/pubmed/28944845 http://dx.doi.org/10.3892/mmr.2017.7518 |
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