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Shear stress induces human aortic endothelial cell apoptosis via interleukin-1 receptor-associated kinase 2-induced endoplasmic reticulum stress

Atherosclerosis is characterized by localized lesions distributed in the arterial tree due to the shear stress produced by blood flow. Endothelial cells are directly affected by alterations in blood flow. Dysfunction and injury to endothelial cells has been hypothesized to initiate the pathological...

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Detalles Bibliográficos
Autores principales: Pan, Longfei, Hong, Zhou, Yu, Lei, Gao, Yanxia, Zhang, Rui, Feng, Hui, Su, Lijuan, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865847/
https://www.ncbi.nlm.nih.gov/pubmed/28944871
http://dx.doi.org/10.3892/mmr.2017.7524