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Nutrient deprivation induces apoptosis of nucleus pulposus cells via activation of the BNIP3/AIF signalling pathway

Nutrient deprivation (ND)-induced nucleus pulposus (NP) cell death serves an important role in intervertebral disc degeneration disease. However, the underlying mechanisms have yet to be thoroughly elucidated. The present study created a cell culture model under ND conditions to investigate the role...

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Detalles Bibliográficos
Autores principales: Liu, Jie, Yuan, Chao, Pu, Luqiao, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865853/
https://www.ncbi.nlm.nih.gov/pubmed/28944876
http://dx.doi.org/10.3892/mmr.2017.7550