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Glucosylceramide synthase regulates the proliferation and apoptosis of liver cells in vitro by Bcl-2/Bax pathway

Our previous study found that glucosylceramide, a type of sphingolipids, was associated with liver inflammation and fibrosis. Glucosylceramide is generated by glucosylceramide synthase (GCS), which is encoded by the UDP-glucose ceramide glucosyltransferase (UGCG) gene. GCS is a key enzyme to regulat...

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Detalles Bibliográficos
Autores principales: Li, Jun-Feng, Zheng, Su-Jun, Wang, Li-Li, Liu, Shuang, Ren, Feng, Chen, Yu, Bai, Li, Liu, Mei, Duan, Zhong-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865865/
https://www.ncbi.nlm.nih.gov/pubmed/28944894
http://dx.doi.org/10.3892/mmr.2017.7580