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Mild hypothermia pretreatment protects against liver ischemia reperfusion injury via the PI3K/AKT/FOXO3a pathway

Mild hypothermia is known to protect against ischemia and reperfusion (IR) injury. The exact mechanisms of the protection are not fully understood. Forkhead box O3 (FOXO3a) has been defined as a critical mediator in cellular processes, including oxidative stress, apoptosis, inflammation, cell death...

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Detalles Bibliográficos
Autores principales: Xiao, Qi, Ye, Qifa, Wang, Wei, Xiao, Jiansheng, Fu, Biqi, Xia, Zhiping, Zhang, Xingjian, Liu, Zhongzhong, Zeng, Xianpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865885/
https://www.ncbi.nlm.nih.gov/pubmed/28944825
http://dx.doi.org/10.3892/mmr.2017.7501