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Depletion of aquaporin 1 decreased ADAMTS-4 expression in human chondrocytes

Inflammation serves an important role in the progression of osteoarthritis (OA), and IL-1β may act as a catabolic factor on cartilage, reducing the synthesis of primary cartilage components type II collagen and aggrecan. Aquaporin 1 (AQP1) is a 28-kDa water channel formed of six transmembrane domain...

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Detalles Bibliográficos
Autores principales: Haneda, Masahiko, Hayashi, Shinya, Matsumoto, Tomoyuki, Hashimoto, Shingo, Takayama, Koji, Chinzei, Nobuaki, Kihara, Shinsuke, Takeuchi, Kazuhiro, Nishida, Kotaro, Kuroda, Ryosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865946/
https://www.ncbi.nlm.nih.gov/pubmed/29393494
http://dx.doi.org/10.3892/mmr.2018.8545