Paeoniflorin induces G2/M cell cycle arrest and caspase-dependent apoptosis through the upregulation of Bcl-2 X-associated protein and downregulation of B-cell lymphoma 2 in human osteosarcoma cells

Paeoniflorin (PF), extracted from the peony root, has been proved to possess antineoplastic activity in different cancer cell lines. However, it remains unclear whether PF has an antineoplastic effect against osteosarcoma cells. The present study investigated the effects and the specific mechanism o...

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Detalles Bibliográficos
Autores principales: Jin, Li-Bin, Zhu, Jian, Liang, Cheng-Zhen, Tao, Li-Jiang, Liu, Bing, Yu, Wei, Zou, Han Hui, Wang, Jun-Jie, Tao, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865973/
https://www.ncbi.nlm.nih.gov/pubmed/29363721
http://dx.doi.org/10.3892/mmr.2018.8464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865973/
https://www.ncbi.nlm.nih.gov/pubmed/29363721
http://dx.doi.org/10.3892/mmr.2018.8464

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